I have been having issues with Profiles on the Site collections not giving updated information.
The context of the problem is as follows;
A particular web part was added to a site, this webpart was expected to display the names and photos of staff in a particular group that was selected for the web part.
The web part worked but did not display so particular profiles photos. Also when you click on the user profile it takes you to a user profile display page "userdisp.aspx" which does not display updated profile.
The fix is a simple one and would require adding some settings to all the site collections.
1. Login to any Site Collection as Admin
2. Click Site Actions >Site Settings>Modify All Site Settings
3. Click Profile Site Connection under Site Collection Administration
4. Select Connect to a portal Site and add https://mysite.domain.com
5. Ok and exit